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SAFETYTirzepatide (Mounjaro/Zepbound) — 140,435 adverse-event reportsFDA CLEAREDIntense Pulsed Light Therapy Device — Sanhe LEFIS Electronics Co., Ltd.Bausch Health (Solta) -8.71%SAFETYSemaglutide (Wegovy/Ozempic) — 82,911 adverse-event reportsFDA CLEAREDBarbed PDO Suture — Sutura Medical Technology, Inc.STRATA Skin Sciences +8.33%SAFETYBotox — 75,499 adverse-event reportsFDA CLEAREDERBECRYO 2 Cryosurgical Unit and Accessories — Erbe Elektromedizin GmbHThe Beauty Health Company (HydraFacial) -7.17%FDA CLEAREDLumiGlam Laser System (SHE-LSP601-3) — Beijing Sano Laser S&T Development Co.,LtdEli Lilly +7.04%FDA CLEAREDCurrentBody Skin LED Multi Light Therapy Mask (MK-110D) — The Beauty Tech Group, Ltd.STAAR Surgical -5.13%RECALLFDA recall: PAYLESS COMPOUNDERS, LLC — Semaglutide-Glycine-Cyanocobalamin Injectable, 2.5 RECALLFDA recall: HTO Nevada Inc. dba Kirkman — MAXIMUM, ZONE 1, 4% Lidocaine Cream, 1/2 oz bottRECALLFDA recall: Pro Numb Tattoo Numbing Spray LLC — Pro Numb Tattoo Numbing Spray, For Sensiti
Soothing & Repair

Centella Asiatica (Cica)

Healing plant extract that soothes, strengthens skin barrier, and reduces redness.

Also known as: Centella asiatica, Cica, Gotu kola, Hydrocotyle asiatica, INCI: Centella Asiatica Extract

What it is
Centella asiatica is a tropical plant native to Asia, traditionally used in Ayurvedic and Chinese medicine. The extract contains bioactive compounds including asiaticoside, madecassoside, and flavonoids that support skin healing and barrier function.
What it does
Cica reduces inflammation and redness by modulating immune response and calming irritated skin. It stimulates collagen and elastin production, strengthens the skin barrier, and accelerates wound healing and tissue repair. It also has mild antioxidant properties that protect against environmental stress.
The evidence
Strong clinical evidence supports its use for soothing irritation, reducing redness, and supporting barrier repair; multiple studies confirm efficacy in post-procedure healing and eczema-prone skin. Moderate evidence for collagen stimulation and anti-aging benefits.
Best for
Sensitive, reactive, compromised, or post-procedure skin; rosacea, eczema, and barrier-repair needs; all skin types benefit from its calming action.
Pairs well with
Hyaluronic acid, niacinamide, panthenol, ceramides, and gentle hydrating ingredients; works well in layered routines with other soothing actives like allantoin or beta-glucan.
Use cautiously with
No major conflicts; generally safe to combine with most ingredients. Use cautiously with high-strength exfoliants or vitamin C on very compromised skin to avoid over-stimulation.
Cautions
Generally well-tolerated; rare allergic contact dermatitis reported in sensitive individuals. Safe during pregnancy and breastfeeding. Not sun-sensitizing; no prescription interactions.
General information, not medical advice. Ingredient effects vary by formulation, concentration, and skin. Patch-test new actives and consult a qualified provider before starting prescription ingredients.

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