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SAFETYTirzepatide (Mounjaro/Zepbound) — 140,435 adverse-event reportsFDA CLEAREDIntense Pulsed Light Therapy Device — Sanhe LEFIS Electronics Co., Ltd.Bausch Health (Solta) -8.71%SAFETYSemaglutide (Wegovy/Ozempic) — 82,911 adverse-event reportsFDA CLEAREDBarbed PDO Suture — Sutura Medical Technology, Inc.STRATA Skin Sciences +8.33%SAFETYBotox — 75,499 adverse-event reportsFDA CLEAREDERBECRYO 2 Cryosurgical Unit and Accessories — Erbe Elektromedizin GmbHThe Beauty Health Company (HydraFacial) -7.17%FDA CLEAREDLumiGlam Laser System (SHE-LSP601-3) — Beijing Sano Laser S&T Development Co.,LtdEli Lilly +7.04%FDA CLEAREDCurrentBody Skin LED Multi Light Therapy Mask (MK-110D) — The Beauty Tech Group, Ltd.STAAR Surgical -5.13%RECALLFDA recall: PAYLESS COMPOUNDERS, LLC — Semaglutide-Glycine-Cyanocobalamin Injectable, 2.5 RECALLFDA recall: HTO Nevada Inc. dba Kirkman — MAXIMUM, ZONE 1, 4% Lidocaine Cream, 1/2 oz bottRECALLFDA recall: Pro Numb Tattoo Numbing Spray LLC — Pro Numb Tattoo Numbing Spray, For Sensiti
Soothing & Repair

Aloe Vera

Gel-rich succulent leaf extract that soothes and hydrates skin.

Also known as: Aloe barbadensis leaf juice, aloe vera gel, aloe extract

What it is
Aloe vera is a succulent plant whose inner leaf gel contains water, polysaccharides, amino acids, and compounds like acemannan. The gel is extracted and used in skincare as a hydrating and soothing agent.
What it does
Aloe vera hydrates the skin, reduces inflammation, and promotes a cooling sensation on irritated or sun-exposed skin. Its polysaccharides form a moisture-binding film, while its antioxidant and anti-inflammatory compounds help calm redness and support the skin barrier. It may also support wound healing and collagen remodeling.
The evidence
Moderate evidence supports its anti-inflammatory and hydrating effects; strong evidence for soothing sunburned or irritated skin. Clinical studies confirm benefit for minor burns and post-procedure redness, though evidence for deep collagen stimulation is emerging and limited.
Best for
Sensitive, irritated, sunburned, or post-procedure skin; all skin types benefit from its hydrating and calming properties.
Pairs well with
Hyaluronic acid, ceramides, centella asiatica, chamomile, niacinamide, and other soothing or hydrating actives.
Use cautiously with
No major conflicts; however, avoid combining with strong acids or retinoids in the same step on very sensitive skin to prevent over-irritation.
Cautions
Rare contact allergy or irritation in sensitive individuals; latex (from the leaf latex, not the gel) can cause GI upset if ingested but is not a topical concern. Generally safe during pregnancy when used topically.
General information, not medical advice. Ingredient effects vary by formulation, concentration, and skin. Patch-test new actives and consult a qualified provider before starting prescription ingredients.

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