Who can legally inject Botox and dermal fillers in Colorado?

MD/DO, NP/PA with physician collaboration, RN under physician delegation Yes, under physician delegation; specific scope varies by facility protocol

Colorado · Moderate

Who Can Inject Botox & Fillers in Colorado?

In Colorado, the answer comes down to two things: who is allowed to hold the syringe, and who has to authorize the treatment first. Here's how Colorado handles both.

By Evan at Inside MedSpa

Who can inject

MD/DO, NP/PA with physician collaboration, RN under physician delegation

Registered nurses (RNs)

Yes, under physician delegation; specific scope varies by facility protocol

Nurse practitioners & physician assistants

NP/PA may inject with physician collaboration; some independent authority in limited contexts

The exam that makes it legal

Required; in-person or telehealth permitted under certain conditions A valid order or good-faith exam by an authorized provider is what makes an injection lawful — not simply who holds the syringe.

Training expected

No state-mandated injector training beyond licensure

What to verify in Colorado

Confirm with the Colorado Medical Board whether your specific ownership structure and delegation model complies with current interpretations of physician collaboration requirements.

Primary source: Colorado Medical Board, Colorado Board of Nursing

General business information for Colorado medical-spa owners, current as of 2026 — not legal advice. State boards update rules often; confirm specifics with the Colorado board (and your own counsel) before you act.

See the full Colorado regulation profile →

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