Can registered nurses and nurse practitioners inject Botox and fillers in Colorado?

Yes, under physician delegation; specific scope varies by facility protocol NP/PA may inject with physician collaboration; some independent authority in limited contexts

Colorado · Moderate

Can RNs and Nurse Practitioners Inject Botox in Colorado?

Nurses do most of the injecting in this industry — but Colorado draws specific lines around what an RN versus an NP can do, and who has to supervise.

By Evan at Inside MedSpa

Registered nurses (RNs)

Yes, under physician delegation; specific scope varies by facility protocol

Nurse practitioners & physician assistants

NP/PA may inject with physician collaboration; some independent authority in limited contexts

Supervision & the medical director

Required for medical spa operations

The exam requirement

Required; in-person or telehealth permitted under certain conditions

What to verify in Colorado

Confirm with the Colorado Medical Board whether your specific ownership structure and delegation model complies with current interpretations of physician collaboration requirements.

Primary source: Colorado Medical Board, Colorado Board of Nursing

General business information for Colorado medical-spa owners, current as of 2026 — not legal advice. State boards update rules often; confirm specifics with the Colorado board (and your own counsel) before you act.

See the full Colorado regulation profile →

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