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SAFETYTirzepatide (Mounjaro/Zepbound) — 140,435 adverse-event reportsFDA CLEAREDIntense Pulsed Light Therapy Device — Sanhe LEFIS Electronics Co., Ltd.Bausch Health (Solta) -8.71%SAFETYSemaglutide (Wegovy/Ozempic) — 82,911 adverse-event reportsFDA CLEAREDBarbed PDO Suture — Sutura Medical Technology, Inc.STRATA Skin Sciences +8.33%SAFETYBotox — 75,499 adverse-event reportsFDA CLEAREDERBECRYO 2 Cryosurgical Unit and Accessories — Erbe Elektromedizin GmbHThe Beauty Health Company (HydraFacial) -7.17%FDA CLEAREDLumiGlam Laser System (SHE-LSP601-3) — Beijing Sano Laser S&T Development Co.,LtdEli Lilly +7.04%FDA CLEAREDCurrentBody Skin LED Multi Light Therapy Mask (MK-110D) — The Beauty Tech Group, Ltd.STAAR Surgical -5.13%RECALLFDA recall: PAYLESS COMPOUNDERS, LLC — Semaglutide-Glycine-Cyanocobalamin Injectable, 2.5 RECALLFDA recall: HTO Nevada Inc. dba Kirkman — MAXIMUM, ZONE 1, 4% Lidocaine Cream, 1/2 oz bottRECALLFDA recall: Pro Numb Tattoo Numbing Spray LLC — Pro Numb Tattoo Numbing Spray, For Sensiti
Sun Protection

Avobenzone

Broad-spectrum UVA absorber; degrades under sun exposure.

Also known as: Butyl methoxydibenzoylmethane, 1-(4-methoxyphenyl)-3-(4-tert-butylphenyl)propane-1,3-dione, Parsol 1789

What it is
Avobenzone is a lipophilic (oil-soluble) organic UV filter that absorbs UVA radiation, particularly in the UVA-I range (340–400 nm). It is one of the few approved broad-spectrum UVA absorbers in sunscreen formulations.
What it does
Avobenzone absorbs UVA rays and converts them into heat, protecting skin from photodamage, premature aging, and skin cancer risk. However, it is photounstable—it degrades when exposed to sunlight—reducing its protective efficacy over time unless stabilized by other ingredients or frequent reapplication.
The evidence
Strong clinical evidence supports avobenzone's UVA absorption and photoprotection. Moderate evidence shows it degrades significantly within 30–60 minutes of sun exposure; stabilizers (e.g., octocrylene, avobenzone-stabilizing polymers) improve photostability. It is FDA-approved and widely used in broad-spectrum sunscreens.
Best for
All skin types requiring UVA protection; essential for photosensitive individuals, those with melasma or post-inflammatory hyperpigmentation, and anyone seeking broad-spectrum (UVA + UVB) coverage.
Pairs well with
Octocrylene, titanium dioxide, zinc oxide, octinoxate, and avobenzone-stabilizing agents (e.g., Helioplex, Mexoryl SX) to enhance photostability and broad-spectrum protection.
Use cautiously with
Avoid pairing with unstabilized formulations or products prone to separation; avobenzone can interact with certain preservatives or chelating agents if not properly formulated. Reapply frequently (every 2 hours) as it degrades in sunlight.
Cautions
Avobenzone is photounstable and loses efficacy with sun exposure; reapplication is critical. Rare contact sensitization reported in sensitive individuals. Not recommended as the sole UVA filter without stabilizers. Pregnancy: generally recognized as safe, but consult a healthcare provider if concerned.
General information, not medical advice. Ingredient effects vary by formulation, concentration, and skin. Patch-test new actives and consult a qualified provider before starting prescription ingredients.

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