Botox and Xeomin are both FDA-cleared botulinum toxin Type A (BoNT-A) neuromodulators, but they are not interchangeable. The critical difference lies in their formulation: Botox is complexed with accessory proteins (100 units per 1 mL vial), while Xeomin is a naked toxin—stripped of those proteins during manufacturing. That distinction drives differences in onset speed, dosing requirements, patient response, and your acquisition cost.

Formulation and the Protein Complex Question