Who can inject

MD/DO, NP/PA under physician supervision, RN under physician delegation.

Registered nurses (RNs)

Yes, under physician delegation; Ohio permits RN injection of neurotoxins and fillers with proper supervision.

Nurse practitioners & physician assistants

NP/PA may inject under physician supervision; independent practice for injectables not permitted.

The exam that makes it legal

Required; in-person exam expected before treatment. A valid order or good-faith exam by an authorized provider is what makes an injection lawful — not simply who holds the syringe.

Training expected

No state-mandated injector training beyond licensure; manufacturer training recommended.

What to verify in Ohio

Establish a written supervision agreement with a licensed Ohio physician and document all delegation protocols for RN/NP/PA injectors.

Primary source: Ohio State Medical Board / Ohio Board of Nursing

General business information for Ohio medical-spa owners, current as of 2026 — not legal advice. State boards update rules often; confirm specifics with the Ohio board (and your own counsel) before you act.

See the full Ohio regulation profile →