Registered nurses (RNs)
Yes, under physician delegation; specific protocols and supervision requirements vary by board interpretation.
Nurse practitioners & physician assistants
NP/PA may inject under physician supervision; independent practice for injectables not clearly permitted.
Supervision & the medical director
Required for medical spa operations; physician supervision of delegated tasks is mandatory.
The exam requirement
Required; in-person exam generally expected before treatment.
What to verify in North Carolina
Establish a written delegation agreement with a supervising physician and document all protocols for RN/NP/PA injector oversight.
Primary source: North Carolina Medical Board / Board of Nursing
General business information for North Carolina medical-spa owners, current as of 2026 — not legal advice. State boards update rules often; confirm specifics with the North Carolina board (and your own counsel) before you act.