Who can inject
MD/DO, NP/PA under physician supervision, RN under physician delegation
Registered nurses (RNs)
Yes, under direct physician delegation and supervision
Nurse practitioners & physician assistants
NP/PA may inject under physician supervision; independent practice limited
The exam that makes it legal
Required; in-person exam mandatory before treatment A valid order or good-faith exam by an authorized provider is what makes an injection lawful — not simply who holds the syringe.
Training expected
No state-mandated injector training beyond licensure, but employer protocols typically required
What to verify in California
Verify physician supervision requirements and ensure compliance with California's strict corporate practice of medicine doctrine before opening.
Primary source: California Medical Board, California Board of Registered Nursing
General business information for California medical-spa owners, current as of 2026 — not legal advice. State boards update rules often; confirm specifics with the California board (and your own counsel) before you act.