PRP vs PRF in Aesthetics: Preparation, Clinical Uses, and Evidence
Both platelet-rich plasma and platelet-rich fibrin are autologous biologics, but their preparation, handling, and clinical profile differ meaningfully—and so does the evidence supporting them.
PRP (platelet-rich plasma) and PRF (platelet-rich fibrin) are both autologous blood-derived products used in aesthetic medicine, but they are prepared differently, behave differently in tissue, and carry distinct clinical profiles. Understanding the distinction is essential for practices considering these treatments and for setting realistic patient expectations.
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